Fig. 1.

Apoptotic neutrophils decreased M. tuberculosis growth both in single and HIV-coinfected macrophages. Human macrophages were preinfected with/without HIV for 7 days before infection with M. tuberculosis (Mtb, MOI = 1) for 1.5 h. After a wash, apoptotic neutrophils (ApoN) were added for 5 days and the signals from luciferase expressing M. tuberculosis in cell lysates (a) and total bacteria (supernatant + lysate; b) were measured. Data are the mean ± SEM from 4 independent experiments. * p < 0.05, ** p < 0.01, using repeated-measures ANOVA.