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. 2020 May 27;11:1110. doi: 10.3389/fmicb.2020.01110

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Copyright © 2020 Li, Peng, Burrough, Sahin, Gould, Gabler, Loving, Dorman and Patience.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Predicted functional metagenomes of ileal digesta microbiota of pigs fed (A) control diet without ETEC (NC) and with ETEC (PC); (B) PC and soluble fiber diet with carbohydrases (SF+); (C) PC and insoluble fiber diet without carbohydrases (IF-); (D) PC and insoluble fiber diet with enzymes (IF+). Linear discriminant analysis (LDA) was performed to identify significant changes in the proportion of reconstructed functional pathways obtained from PICRUSt predictive algorithms at Kyoto Encyclopedia of Genes and Genomes (KEGG). Analysis was performed using linear discriminant analysis of effect size (LEfSe).