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. 2020 May 27;11:1110. doi: 10.3389/fmicb.2020.01110

TABLE 1.

Effect of soluble or insoluble fiber diet without or with carbohydrases on intestinal volatile fatty acids (VFA) in weaned pigs challenged with ETEC F18a.

Item Treatmentb SEM Contrast P-valuec


NC PC SF IF Fiber Enzyme F × E


SF− SF+ IF− IF+
Cecal VFA, μmol/g digesta
Acetate 67.6 54.8 67.1 76.2* 44.0 40.0 5.4 <0.001 0.214 0.713
Propionate 42.6* 30.5 31.6 32.0 25.8 25.0 3.3 0.061 0.940 0.853
Butyrate 18.5 13.6 16.4 14.8 13.0 11.8 2.6 0.228 0.595 0.932
Valerate 3.7# 2.2 2.5 0.9 2.0 1.8 0.6 0.758 0.033 0.580
Total 132.4* 101.0 117.6 123.8 84.8 86.8 10.2 0.002 0.694 0.839
pH 5.59 5.55 5.41 5.18 5.44 5.58 0.24 0.219 0.785 0.282
Colonic VFA, μmol/g digesta
Acetate 62.2# 53.5 66.7* 64.9* 59.1 53.4 3.1 0.005 0.240 0.543
Propionate 22.8# 16.9 23.0* 18.6 20.4 16.6 2.0 0.256 0.046 0.870
Butyrate 12.5 9.5 15.4* 12.5 11.0 9.8 1.6 0.021 0.169 0.542
Valerate 4.2* 3.0 4.1# 3.1 3.6 2.8 0.4 0.349 0.025 0.831
Isobutyrate 2.0 1.8 0.7* 1.4 1.1 1.3 0.3 0.711 0.164 0.443
Isovalerate 3.6* 2.5 1.5# 2.3 2.0 2.3 0.4 0.524 0.152 0.414
Total 107.3* 87.1 111.7* 102.8# 97.3 86.2 5.9 0.014 0.106 0.858
pH 5.96 6.22 5.93# 5.64* 5.95# 5.91# 0.16 0.212 0.154 0.270

*Indicate significant difference compared to PC (P ≤ 0.05). #Indicate tendency for significant difference compared to PC (0.05 < P ≤ 0.10). an = 10 pigs per treatment. bNC, non-challenged control diet; PC, ETEC-challenged control diet; SF, soluble fiber diets without or with carbohydrases; IF, insoluble fiber diets without or with carbohydrases; SF-, soluble fiber diet without carbohydrases; SF+, soluble fiber diet with carbohydrases; IF-, insoluble fiber diet without carbohydrases; IF+, insoluble fiber diet with carbohydrases. cFiber, dietary fiber type effect (SF vs. IF); Enzyme, carbohydrase effect (without vs. with); F × E, fiber type by carbohydrase interaction effect.