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. 2020 May 7;26(17):2064–2081. doi: 10.3748/wjg.v26.i17.2064

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Pathological changes in different groups. A: Dimethylhydrazine (DMH) + low-dose epigallocatechin gallate (EGCG) group showed moderate to severe dysplasia and local carcinogenesis (Hematoxylin-eosin staining, × 100); B: DMH + low-dose EGCG group showed moderate to severe dysplasia and local carcinogenesis (Hematoxylin-eosin staining, × 400); C: DMH + medium-dose EGCG group showed moderate to severe dysplasia (Hematoxylin-eosin staining, × 100); D: DMH + medium-dose EGCG group showed moderate to severe dysplasia (Hematoxylin-eosin staining, ×400); E: DMH + high-dose EGCG group showed chronic inflammation (Hematoxylin-eosin staining, × 100); F: DMH + high-dose EGCG group showed chronic inflammation (Hematoxylin-eosin staining, × 400); G: DMH group showed signet-ring cell carcinoma (Hematoxylin-eosin staining, × 100); H: DMH group showed signet-ring cell carcinoma (Hematoxylin-eosin staining, × 400).