Table 1.
Clinical and biological baseline characteristics of nonobese and obese patients enrolled in the study
| nonobese (n= 10) | obese (n= 26) | p value obese vs nonobese | |
|---|---|---|---|
| Demographic data | |||
| sex ratio M/F, % | 100/0 | 4/96 | <0.0001 |
| age (years) | 58.8 ± 4.9 (42–84) | 39.3 ± 2.3 (21–64) | 0.0002 |
| Corpulence and adiposity | |||
| weight (kg), mean ± SEM (min–max) | 69.5 ± 3.2 (50–87) | 124.3 ± 4.7 (83.1–184.4) | <0.0001 |
| BMI (kg/m2), mean ± SEM (min–max) | 22.6 ± 0.82 (16.9–26.37) | 46.5 ± 1.3 (38.1–56.9) | <0.0001 |
| Comorbidities | |||
| type 2 diabetes, % | 0 | 0 | – |
| dyslipidemia, % | 16 | 90 | 0.0164 |
| hypertension, % | 0 | 25 | 0.1310 |
| Glucose metabolism | |||
| glycemia (mmol/L), mean ± SEM (min–max) | – | 5.3 ± 0.1 (4.3–6.4) | – |
| insulinemia (mU/L), mean ± SEM (min–max) | – | 25.1 ± 3.9 (9.5–67.5) | – |
| HOMA-IR index, mean ± SEM (min–max) | – | 6.3 ± 1.1 (2.4–18.7) | – |
| Lipid metabolism | |||
| total cholesterol (mmol/L), mean ± SEM (min–max) | – | 5.0 ± 0.2 (3.3–7.2) | – |
| triglycerides (mmol/L), mean ± SEM (min–max) | – | 1.3 ± 0.08 (0.47–1.96) | – |
| HDL (mmol/L), mean ± SEM (min–max) | – | 1.1 ± 0.06 (0.7–1.6) | – |
| LDL (mmol/L), mean ± SEM (min–max) | – | 3.3 ± 0.2 (1.9–5.2) | – |