. 2020 May 4;17:1178–1189. doi: 10.1016/j.omtm.2020.04.022

Table 2.

mRNA Analysis of Mstn Levels across Cohorts

Study Number	Tissue	Group
Study Number	Tissue	WT	Mtm1^−/y	Mtm1^−/y+ Reduced Dnm2
1	TA	1.04 ± 0.09 (10)	0.19 ± 0.03 (5)^a	0.25 ± 0.03 (9)^a
	GAS	1.03 ± 0.13 (5)	0.27 ± 0.01 (2)^a	0.83 ± 0.22 (5)
	heart	1.43 ± 0.50 (5)	0.92 ± 0.25 (2)	1.56 ± 0.29 (5)
2	TA	1.00 ± 0.17 (6)	0.32 ± 0.09 (4)^a	0.42 ± 0.07 (8)^a
3	TA	1.01 ± 0.14 (2)	0.20 ± 0.03 (5)	0.22 ± 0.03 (5)
	GAS	1.02 ± 0.19 (2)	0.45 ± 0.04 (5)	0.64 ± 0.19 (5)
	heart	1.14 ± 0.55 (2)	1.24 ± 0.35 (5)	0.80 ± 0.12 (5)
	soleus	1.03 ± 0.25 (2)	0.79 ± 0.37 (5)	0.98 ± 0.22 (5)
	diaphragm	1.03 ± 0.23 (2)	0.22 ± 0.06 (5)^a	0.53 ± 0.03 (5)^a^,^b
	EDL	1.00 ± 0.07 (2)	0.15 ± 0.03 (5)^a	0.36 ± 0.04 (5)^a^,^b
4, analyzed at 2 weeks	TA	1.00 ± 0.03 (4)	0.68 ± 0.08 (4)^a	0.63 ± 0.08 (4)^a
4, analyzed at 7 weeks	TA	1.00 ± 0.10 (5)	0.27 ± 0.06 (5)^a	0.50 ± 0.06 (4)^a

Mstn mRNA analysis relative to Rpl27 expression from various cohorts. Mean ± SEM represented, number of mice (n) indicated. See Figure S4 for violin plots.

Significant difference from WT.

Significant difference from Mtm1^−/y.