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. 2020 May 13;39:101009. doi: 10.1016/j.molmet.2020.101009

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of HD and baricitinib administration on the kidneys. Acid-Schiff positive staining within the glomeruli (an indicator of mesangial expansion) (A, B and C) and histological analysis of kidney sections (D, Eand F). Bowman's capsule area (G), glomerular area (H), urinary albumin creatinine ratios (ACR; I), and expression level of cyclin kinase inhibitor (p21, L) were evaluated in the kidneys of the mice exposed to ND or HD in the absence or presence of baricitinib (10 mg/kg die, p.o.). Values are mean ± SEM for n = 6 per group. ∗p<0.05 vs ND and •p<0.05 vs HD.