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Effect of CFTR modulation on community composition. Dissimilarities in bacterial genera using log transformed counts are shown for children with CF receiving CFTR modulators (CFTR_Y), children with CF not receiving CFTR modulators (CFTR_N), and age similar healthy controls (HC). (A) Bray-Curtis distance PCoA (PERMANOVA R2 = 0.071, p > 0.999). (B) Jaccard distance PCoA (PERMANOVA R2 = 0.058, p > 0.999).
