Table 2.
Alpha diversity Measures between children with CF and healthy controls.
| Cystic Fibrosis (n = 25)† | Healthy Control (n = 50)† | P value† | Cystic Fibrosis (n = 25)‡ | Healthy Control (n = 50)‡ | P value‡ | |
|---|---|---|---|---|---|---|
| Number of OTUs∗ (mean, standard error) | 62.1 (7.4) | 83 (4.4) | 0.022 | 36.0 (3.2) | 43.0 (1.9) | 0.080 |
| Shannon Diversity Index∗ (mean, standard error) | 2.09 (0.11) | 2.35 (0.07) | 0.057 | 2.07 (0.11) | 2.34 (0.07) | 0.054 |
| Inverse Simpson Index∗ (mean, standard error) | 5.70 (0.63) | 6.92 (0.38) | 0.118 | 5.70 (0.63) | 6.92 (0.38) | 0.118 |
OTUs, operational taxonomic units.
∗
Generalized linear model, adjusting for age, race, ethnicity, length of breastfeeding, and siblings.
†
Using all available sequencing data.
‡
Using subsampled sequencing data (2043 sequences).