Table 2.
Success rate and complications of studies included in meta-analysis.
| Author, year | Number of eyes at baseline | Number of eyes at end point | Success rate | Complication rate | ||
|---|---|---|---|---|---|---|
| IOP ≤18 mmHg (n, %) | IOP reduction ≥20% (n, %) | Event (n, %) | Types of complication (%) | |||
| Buznego, 2008 [17] | 41 | 41 | 41 (100) | NR | 6 (15) | Malposition (15) |
| Ahmed et al., 2014 [18] | 39 | 39 | 39 (100) | 39 (100) | 0 (0) | None |
| Fea et al., 2014 [19] | 94 | 94 | 87 (92.6) | 89 (94.7) | 3 (3) | IOP decompensation (1), one stent not visible (1), soreness/discomfort (1) |
| Voskanyan et al., 2014 [20] | 99 | 88 | 71 (80.7) | 82 (93.2) | 35 (35.3) | Elevated IOP (10.1), iStent obstruction (3), progression of cataract (1), allergic reaction to medications (1), iStent malposition (1), intraocular inflammation (1), subconjunctival hemorrhage (1), iStent not visible upon gonioscopy (13.1), posterior capsular opacification (2), goniosynechiae (1), lens-iris synechiae (1) |
| Donnenfeld et al., 2015 [21] | 39 | 29 | 26 (89.7) | 25 (86.2) | 10 (25.6) | Progression of cataract (7.7), death (5.1), hyphema (2.6), initial cataract (2.6), proliferative diabetic retinopathy (2.6), scar from age-related macular degeneration (2.6), cataract surgery (2.6) |
| Katz et al., 2015 [22] | 38 (1 device) | 37 | 33 (89.2) | 33 (89.2) | 2 (5.3) | Cataract surgery (5.3) |
| 41 (2 devices) | 41 | 37 (90.2) | 37 (90.2) | 0 (0) | None | |
| 40 (3 devices) | 38 | 35 (92.1) | 35 (92.1) | 2 (5.3) | Cataract surgery (5.3) | |
| Klamann et al., 2015 [23] | 17 (POAG) | 17 | NR | NR | 32 (91.4) | Intraoperative blood reflux (91.4) |
| 15 (PEX) | 15 | NR | NR | |||
| 3 (PG) | 3 | NR | NR | |||
| Ferguson et al., 2016 [24] | 42 | 42 | NR | NR | 1 (2.4) | Elevated IOP (2.4) |
| Lindstrom et al., 2016 [25] | 57 | 57 | 57 (100) | 43 (75.4) | 1 (1.8) | Progression of cataract (1.8) |
| Vold et al., 2016 [26] | 54 | 34 | 31 (91.1) | NR | 12 (22.2) | Progression of cataract (20.4), hyphema (1.8) |
| Berdahl et al., 2017 [27] | 53 | 53 | 46 (86.8) | 48 (90.6) | 0 (0) | None |
| Chang et al., 2017 [28] | 39 | 35 | 30 (85.7) | 34 (97.1) | 13 (33.3) | Transient hypotony (5.1), progression of cataract (23.1), insomnia/malaise (2.6), herpetic corneal ulcer (2.6) |
| Pahlitzsch et al., 2017 [29] | 20 | 20 | NR | NR | NR | NR |
| Shiba et al., 2017 [30] | 10 | 8 | 4 (50) | 4 (50) | 9 (90) | Hyphema (40), elevated IOP (10), peripheral anterior synechiae (40) |
| Katz et al., 2018 [31] | 38 (1 device) | 28 | NR | 17 (60.7) | 8 (21.1) | Progression of cataract (21.1) |
| 41 (2 devices) | 35 | NR | 32 (91.4) | 5 (12.2) | Progression of cataract (12.2) | |
| 40 (3 devices) | 35 | NR | 32 (91.4) | 7 (17.5) | Progression of cataract (17.5) | |
| Ahmed et al., 2019 [32] | 77 | 75 | 43 (57.3) | 10 (13.3) | 15 (19.5) | Elevated IOP (5.2), new cataract (1.3), iStent obstruction (13.0) |
| Hengerer et al., 2019 [33] | 44 | 33 | 32 (97.0) | 29 (87.9) | 4 (9.1) | Mild hyphema (2.3), progression of cataract (4.5), uveitis (2.3) |