Table 1.

Positive correlations of functional connectivity of seed regions from the “probabilistic in vivo atlas” of Pauli et al. under levodopa, compared with placebo (l‐DOPA > placebo and placebo > l‐DOPA)

Seed region	Brain region	Cluster size	MNI‐coordinates			pFDR
			x	y	z
l‐DOPA > placebo
Ca	Gyrus precentralis L, central operculum L	219	60	+2	+4	0.003
SNc	Central operculum L, gyrus precentralis L	746	−50	−14	+10	0.003
	Central operculum R	305	60	–20	+30	0.0004
	Polus temporalis R	150	34	+4	–48	0.019
	Centrale operculum R, insula R	138	48	–2	+12	0.02
	Insula L, central operculum L	113	−34	+0	+12	0.037
	Insula R, frontal operculum R	102	40	+16	–2	0.045
SNr	Precentral gyrus L	339	−46	−6	+28	0.0005
	Gyrus supramarginalis L	251	−56	−52	+36	0.002
	Insula R	225	44	+12	–4	0.002
	Polus temporalis L	197	−56	+12	–6	0.004
	Insula L, central operculum L	156	−34	+0	+12	0.012
	Lateral occipital cortex L	146	−12	−78	+52	0.014
	Central operculum R, parietal operculum R	126	58	–18	+20	0.023
VTA	Central operculum L, insula L	548	−32	+2	+12	0.000002
Placebo > l‐DOPA
Ca	Paracingulate gyrus (L/R), R medial prefrontale cortex	439	−8	+54	+0	0.000009
NAC	Medial prefrontale cortex	113	−2	+50	–18	0.046
EXA	Medial prefrontale cortex	138	−2	+50	–18	0.018

Note: The table shows significant cluster, their size in voxel, and their localization in the MNI space as MNI coordination in the order x y z. The threshold for cluster correction was set at p < .001. Only significant seed regions are shown.

Abbreviations: Pu, putamen; CA, nucleus caudatus, NAC, nucleus accumbens; EXA, extended Amygdala; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticularis; VTA, area tegmentalis ventralis; L, left; R, right.