Table 3.
Positive correlations of functional connectivity of seed regions from the “probabilistic in vivo atlas” of Pauli et al. under levodopa, compared with amisulpride (amisulpride vs. l‐DOPA)
| Seed region | Brain region | Cluster size | MNI‐coordinates | pFDR | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| l‐DOPA > Amisulpride | ||||||
| Pu | Gyrus Fusiformis R, hippocampus R, gyrus parahippocampalis R | 205 | 32 | –20 | –24 | 0.005 |
| NAC | Gyrus temporalis inferior L, lateral occipital cortex L | 228 | −58 | –64 | –12 | 0.002 |
| EXA | Gyrus frontalis medius R | 126 | 40 | +26 | +44 | 0.04 |
| SNc | Cerebellum R | 366 | 18 | –48 | –50 | 0.0002 |
| SNr | Gyrus supramarginalis R, | 644 | 64 | –34 | +44 | 0.000001 |
| Cerebellum R | 522 | 12 | –46 | –62 | 0.000004 | |
| Gyrus supramarginalis L, gyrus postcentralis L | 364 | −48 | –40 | +50 | 0.00008 | |
| Cerebellum L | 286 | −20 | –66 | –58 | 0.0004 | |
| Lateral occipital cortex L | 195 | −22 | –72 | +38 | 0.003 | |
| Amisulpride > l‐DOPA | ||||||
| EXA | Cuneus L, Polus occipitalis L | 334 | −14 | –78 | +20 | 0.00007 |
Note: The table shows significant cluster, their size in voxel, and their localization in the MNI space as MNI coordination in the order x y z. The threshold for clusters was set at p < .001. Only significant seed regions are shown.
Abbreviations: Pu, putamen; CA, nucleus caudatus, NAC, nucleus accumbens; EXA, extended amygdala; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticularis; VTA, area tegmentalis ventralis; L, left; R, right.