Table 4.
Positive correlations of functional connectivity of seed regions from the “probabilistic in vivo atlas” of Pauli et al. under levodopa and amisulpride compared with placebo (l‐DOPA + amisulpride vs. l‐DOPA)
| Seed region | Brain region | Cluster size | MNI‐coordinates | pFDR | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| l‐DOPA + Amisulpride > placebo | ||||||
| Pu | Precuneus | 214 | −02 | −52 | +60 | 0.001 |
| EXA | R inferior frontal gyrus | 136 | +02 | +12 | +20 | 0.02 |
| SNc | Insula L, central operculum R | 154 | −56 | −14 | +8 | 0.02 |
| Insula R, central operculum L | 104 | +46 | –08 | +08 | 0.04 | |
Note: The table shows significant cluster, their size in voxel, and their localization in the MNI space as MNI coordination in the order x y z. The threshold for clusters was set at p < .001. Only significant seed regions are shown.
Abbreviations: Pu, putamen; CA, nucleus caudatus, NAC, nucleus accumbens; EXA, extended Amygdala; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticularis; VTA, area tegmentalis ventralis; L, left; R, right.