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. 2019 Nov 5;41(4):1030–1042. doi: 10.1002/hbm.24858

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© 2019 The Authors. Human Brain Mapping published by Wiley Periodicals, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Association between the activity of the AI and trait empathy. (a) The left and right AI clusters significantly activated in the painful condition as compared to the neutral condition. (b) Bar charts depicting the observed event‐related blood oxygenation level‐dependent signal change (%, mean), calculated based on spherical ROIs of 9 mm radius per condition for painful and neutral photographs in the left and right AI. (c) Scatter plot demonstrating association between the trait empathy and the activity of the left and right AI in painful condition. AI, anterior insula cortex; EC scores, score of the Empathic Concern Subscale; PT scores, score of the Perspective Taking Subscale