Table 2.

Anatomical location and effect sizes (Cohen's d) of group differences in white‐matter metrics

	Region	FA	MD	AD	AD	RD	MTR	Volume
	Group difference	FRDA < CON	FRDA > CON	FRDA > CON	FRDA < CON	FRDA > CON	FRDA < CON	FRDA < CON
Cerebellar tracts	Peri‐dentate white matter
	Superior cerebellar peduncle
	Middle cerebellar peduncle
	Inferior cerebellar peduncle
Projection tracts	Corticospinal tract
	Anterior thalamic radiation
	Posterior thalamic radiation
	Peri‐thalamic WM
Commissural tracts	Corpus callosum (genu)
	Corpus callosum (body)
	Corpus callosum (splenium)
Association tracts	Superior longitudinal fasciculus
	Inferior longitudinal fasciculus/Inferior fronto‐occipital fasciculus (posterior region)
	Uncinate fasciculus
	Fornix
	Cingulum

Note: (d = 0.5–0.99) (d = 1–1.99) (d = 2–2.99) (d = 3–3.99) (d = 4+).

Abbreviations: AD, axial diffusivity; FA, fractional anisotropy; MD, mean diffusivity; MTR, magnetization transfer ratio; RD, radial diffusivity.