Figure 1.

Flowchart of our study design. (a) HDRS total scores were used as a reference to guide a two‐way MRI fusion for all DEP subjects (responders + nonresponders) to identify ECT responsive multimodal brain networks. (b) Back‐reconstruction (BR) was performed on the HC group. Then the same HDRS‐guided fusion was performed on (c) responder and (d) nonresponder subgroups separately to extract specific ECT responsive brain networks. Finally, the correlation between memory scores and the identified ECT responsive multimodal brain networks was examined