Table 3.
Correlation between global WMH load and cognitiona
Rho [95% CI] | p | |
---|---|---|
Cognitive z‐score composites | ||
Episodic memory | −0.07 [−0.156 to 0.001] | 0.04* |
Executive function | −0.07 [−0.152 to 0.012] | 0.04* |
Memory Binding Test | ||
Total free recall | −0.05 [−0.131 to 0.029] | 0.12 |
Total delayed free recall | −0.07 [−0.156 to 0.001] | 0.04* |
Total paired recall | −0.05 [−0.130 to 0.037] | 0.14 |
Total delayed paired recall | −0.07 [−0.155 to −0.001] | 0.04* |
Paired recall pairs | −0.06 [−0.146 to 0.019] | 0.07 |
Pairs in delayed free recall | −0.08 [−0.166 to −0.001] | 0.03* |
Semantic proactive interference | −0.08 [−0.161 to 5.5e−05] | 0.03* |
Subtests of WAIS‐IV | ||
Digit span forward | −0.01[−0.090 to 0.079] | 0.42 |
Digit span backward | −0.09 [−0.174 to −0.001] | 0.01* |
Digit span sequencing | 0.03 [−0.056 to 0.110] | 0.28 |
Coding | −0.06 [−0.135 to 0.023] | 0.08 |
Visual puzzles | −0.01 [−0.095 to 0.070] | 0.39 |
Matrix reasoning | −0.05 [−0.129 to 0.031] | 0.12 |
Similarities | −0.06 [−0.143 to 0.024] | 0.08 |
Cognition adjusted by age, sex, education and number of APOE‐ε4 alleles. WMH also adjusted by TIV.
*p < .05.