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. 2019 Nov 28;41(5):1309–1322. doi: 10.1002/hbm.24877

Table 3.

Correlation between global WMH load and cognitiona

Rho [95% CI] p
Cognitive z‐score composites
Episodic memory −0.07 [−0.156 to 0.001] 0.04*
Executive function −0.07 [−0.152 to 0.012] 0.04*
Memory Binding Test
Total free recall −0.05 [−0.131 to 0.029] 0.12
Total delayed free recall −0.07 [−0.156 to 0.001] 0.04*
Total paired recall −0.05 [−0.130 to 0.037] 0.14
Total delayed paired recall −0.07 [−0.155 to −0.001] 0.04*
Paired recall pairs −0.06 [−0.146 to 0.019] 0.07
Pairs in delayed free recall −0.08 [−0.166 to −0.001] 0.03*
Semantic proactive interference −0.08 [−0.161 to 5.5e−05] 0.03*
Subtests of WAIS‐IV
Digit span forward −0.01[−0.090 to 0.079] 0.42
Digit span backward −0.09 [−0.174 to −0.001] 0.01*
Digit span sequencing 0.03 [−0.056 to 0.110] 0.28
Coding −0.06 [−0.135 to 0.023] 0.08
Visual puzzles −0.01 [−0.095 to 0.070] 0.39
Matrix reasoning −0.05 [−0.129 to 0.031] 0.12
Similarities −0.06 [−0.143 to 0.024] 0.08
a

Cognition adjusted by age, sex, education and number of APOE‐ε4 alleles. WMH also adjusted by TIV.

*p < .05.