Table 1.

The chemical-protein relation (CPR) groups.

Group	Evaluated in the BioCreative VI ChemProt shared task?	ChemProt relations
CPR:1	No	PART_OF
CPR:2	No	REGULATOR|DIRECT_REGULATOR|INDIRECT_REGULATOR
CPR:3	Yes	UPREGULATOR|ACTIVATOR|INDIRECT_UPREGULATOR
CPR:4	Yes	DOWNREGULATOR|INHIBITOR|INDIRECT_DOWNREGULATOR
CPR:5	Yes	AGONIST|AGONIST-ACTIVATOR|AGONIST-INHIBITOR
CPR:6	Yes	ANTAGONIST
CPR:7	No	MODULATOR|MODULATOR-ACTIVATOR|MODULATOR-INHIBITOR
CPR:8	No	COFACTOR
CPR:9	Yes	SUBSTRATE|PRODUCT_OF|SUBSTRATE_PRODUCT_OF
CPR:10	No	NOT