Table 1.
Demographics, clinical information, and CBF values of the subjects
| Parameters | NC (32) | Non‐NPSLE (24) | NPSLE (31) | ANOVA or Kruskal–Wallis H (P) | NC versus non‐NPSLE (P) | NC versus NPSLE (P) | Non‐NPSLE versus NPSLE (P) |
|---|---|---|---|---|---|---|---|
| Age (years) | 32.93 ± 10.75 | 29.13 ± 10.03 | 32.36 ± 12.61 | 0.422a | 0.182b | 0.827b | 0.318b |
| Disease duration(month) | – | 28 (2–120) | 60 (3–468) | – | – | – | 0.090c |
| SLEDAI | – | 4 (0–12) | 6 (0–43) | – | – | – | 0.042c |
| SLICC | – | 0 (0–1) | 1 (0–4) | – | – | – | <0.001c |
| Total cumulative duration of steroid use (month) | – | 22.5 (0–192) | 21.5 (0–468) | – | – | – | 0.408c |
| WM lesion volumes(ml) | – | 6.57 ± 3.08 | 9.29 ± 1.42 | – | – | – | 0.469c |
| WB CBF(ml/100 g/min) | 31.99 ± 4.32 | 36.02 ± 13.63 | 33.65 ± 14.69 | 0.208d | 0.446c | 0.145c | 0.149c |
| GM CBF(ml/100 g/min) | 39.99 ± 5.62 | 43.98 ± 13.77 | 39.95 ± 15.00 | 0.383a | 0.438b | 1b | 0.436b |
| WM CBF(ml/100 g/min) | 19.66 ± 2.54 | 23.76 ± 14.10 | 23.94 ± 14.82 | 0.923d | 0.667c | 0.967c | 0.786 |
| CBF ratio of GM/WM | 2.03 ± 0.13 | 1.99 ± 0.29 | 1.80 ± 0.33 | 0.004d | 1c | 0.002c | 0.009c |
Note: Data were presented by mean ± standard deviation or median(range). More clinical information can refer to Table S1.
a
ANOVA.
b
Post hoc Tukey.
c
Mann–Whitney U test.
d
Kruskal–Wallis H test.