Figure 4.

Effect of the left temporal and left occipital T2w‐lesion (T2LV) on the cortical thickness (CTh) of all multiple sclerosis patients. The gradient from yellow to red indicates a weaker to stronger negative correlation respectively, as shown by the t‐values extracted from our linear mixed effect models. In each graph, the highest (or less negative) gradient value represents the threshold of the respective t‐values after correction with the false discovery rate approach for multiple comparisons set at q < 0.05. Up left: correlation of the average CTh with the average left temporal T2LV. Up right: correlation of the CTh and left temporal T2LV changes over time. The right hemisphere was added in this figure solely for completion, since no correlation between CTh in the right hemisphere and left temporal T2LV changes over time was found. Down left: correlation of the average CTh with the average left occipital T2LV. Up right: correlation of the CTh and left occipital T2LV changes over time