The functional activity was significantly lower in the bilateral inferior temporal gyrus (a, left) and right hippocampus (a, right) and increased in the bilateral lingual gyrus (b). Two correlations survived after multiple‐comparison correction: The functional activity alterations in the right hippocampal gyrus were negatively correlated with anxiety scores (p = .034, false discovery rate corrected, a). The nodal centrality of the left inferior frontal gyrus was positively correlated with positive emotional score during jet lag (p = .0001, false discovery rate corrected, d). Other significant relationships that were nominally significant but did not meet the threshold of multiple‐comparison correction included: A negative correlation between TSH levels and positive emotion scores during jet lag (p = .039, b). Right inferior temporal gyrus activity (p = .044, c) was positively correlated with cortisol levels during jet lag. Positive correlations were found between the brain activity of right lingual gyrus and melatonin (p = .031, e) and TSH (p = .028, f)