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. 2020 Jun 2;16:1744806920930858. doi: 10.1177/1744806920930858

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — NF-κB-selective inhibitor PDTC suppressed chronic visceral pain in NMD rats. (a) Single injection of PDTC (800 ng/kg and 8000 ng/kg) into the ARC area significantly attenuated chronic visceral pain sensitivity of NMD rats (n=5 for each group, *p<0.05, ***p<0.001, two-way ANOVA). (b) Compared with the DMSO group at the same time period, continuous injection of 800 ng/kg PDTC into ARC area for seven consecutive days remarkably attenuated the chronic visceral pain of adult NMD rats (n=6 for each group, ***p<0.001, two-way ANOVA). NMD: neonatal maternal deprivation; PDTC: pyrrolidine dithiocarbamate.