Figure 6.

Overexpression of GRK6 reversed the expression of NF-κB. (a) Compared with LV-NC rats, the protein expression of NF-κB receptor in LV-GRK6 group was significantly reduced (n = 4 for each group, *p < 0.05, two-tailed two-sample t-test). (b) There was no significant alteration in GRK6 protein expression in PDTC-treated group compared with DMSO group (n = 6 for DMSO and n = 5 for PDTC group, p > 0.05, two-tailed two-sample t-test). PDTC: pyrrolidine dithiocarbamate; GRK6: G protein-coupled kinase 6; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; NF-κB: nuclear factor κB; NC: negative control; LV: lentiviral.