Table 1.
Mean demographic characteristics before intervention of postmenopausal women donating thigh-muscle biopsies.
| Healthy (n = 18), mean (SD) |
Osteoporotic (n = 17), mean (SD) |
t-test p-value |
|
|---|---|---|---|
| Age (years) | 73.9 (5.7) | 68.0 (6.2) | 0.460 |
| Body mass (kg) | 68.1 (11.9) | 63.3 (12.1) | 0.288 |
| BMI (weight/height2) | 25.2 (3.6) | 23.8 (4.8) | 0.358 |
| Femoral neck (T-score) | −0.18 (0.76) | −2.35 (0.54) | p < 0.001 |
| L1–L4 BMD (T-score) | 0.49 (1.17) | −3.46 (0.90) | p < 0.001 |
| Total body BMD (T-score) | 0.24 (1.20) | −2.39 (1.14) | p < 0.001 |
| Lean mass (kg) | 40.3 (4.3) | 39.7 (4.5) | 0.712 |
| Fat mass (kg) | 25.5 (8.2) | 21.3 (8.9) | 0.194 |
| Maximal squat load (kg) | 48.3 (3.9) | 21.2 (3.1) | p < 0.001 |
T-score denotes bone mineral density (g calcium/cm2) calculated in relation to a reference population of young healthy adult White women.
BMD, bone mineral density; BMI, body mass index; L1–L4, average BMD of lumbar vertebra 1–4; SD, standard deviation.