Table 3.
Univariate Cox analysis of factors associated with overall survival in early-stage cohort
| Variables | HR (95% CI)a | P |
|---|---|---|
| Age (years) | 1.007 (0.960–1.056) | 0.774 |
| Tumor size (cm) | ||
| ≤ 4 (reference) | 1 | |
| > 4 | 2.750 (1.110–6.814) | 0.029 |
| FIGO stageb | ||
| I (reference) | 1 | |
| II | 0.812 (0.239–2.757) | 0.739 |
| Pathologic types | ||
| Squamous cell carcinoma (reference) | 1 | |
| Adenocarcinoma | 2.605 (0.946–7.171) | 0.064 |
| Adenosquamous carcinoma | 2.583 (0.341–19.558) | 0.358 |
| Differentiation grade | ||
| Well (reference) | 1 | |
| Moderate | 6009.923 (–) | 0.94 |
| Poor | 12,458.308 (–) | 0.935 |
| Stromal invasion | ||
| <1/2 (reference) | 1 | |
| ≥1/2 | 0.681 (0.275–1.687) | 0.406 |
| Lymphovascular space invasion | ||
| No (reference) | 1 | |
| Yes | 3.622 (1.403–9.349) | 0.008 |
| Pelvic lymph node metastasis | ||
| No (reference) | 1 | |
| Yes | 8.297 (3.428–20.078) | < 0.001 |
| Vaginal involvement | ||
| No (reference) | 1 | |
| Yes | 0.049 (0–483,831.748) | 0.713 |
| Parametrial infiltration | ||
| No (reference) | 1 | |
| Yes | 0.049 (0–368,184,919.781) | 0.795 |
| DSG2 | ||
| Low (reference) | 1 | |
| High | 8.679 (2.917–25.822) | < 0.001 |
a95% CI, 95% confidence interval; HR, hazard ratio
bFIGO 2009 was used