Table 4.
GO enrichment analysis results for miR-106a
| BP | ||
|---|---|---|
| GO terms | Genes | P-value |
| Peptidyl-serine phosphorylation | 24 | 7.10E-07 |
| Cell cycle arrest | 16 | 2.07E-06 |
| Regulation of mitotic cell cycle | 10 | 1.51E-05 |
| Negative regulation of TGF-βreceptor signaling pathway | 12 | 1.26E-04 |
| Cellular response to amino acid stimulus | 11 | 1.50E-04 |
| Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 20 | 1.61E-04 |
| Protein autophosphorylation | 19 | 2.91E-04 |
| Transforming growth factor beta receptor signaling pathway | 12 | 7.78E-04 |
| Plus-end-directed vesicle transport along microtubule | 4 | 1.37E-03 |
| Mitochondrial genome maintenance | 5 | 1.43E-03 |
| CC | ||
| GO terms | Genes | P-value |
| Cytoplasm | 269 | 1.64E-14 |
| Nucleus | 255 | 2.89E-10 |
| Nucleoplasm | 136 | 1.40E-07 |
| Membrane | 96 | 6.43E-07 |
| Focal adhesion | 41 | 3.48E-05 |
| Nucleolus | 65 | 5.42E-05 |
| CCR4-NOT complex | 7 | 6.55E-05 |
| Centrosome | 39 | 2.15E-04 |
| Transcription factor complex | 25 | 2.26E-04 |
| Cytoskeleton | 17 | 2.79E-04 |
| MF | ||
| GO terms | Genes | P-value |
| ATP binding | 124 | 1.47E-06 |
| Protein serine/threonine kinase activity | 33 | 4.69E-05 |
| Poly(A) RNA binding | 90 | 2.25E-04 |
| Ubiquitin-protein transferase activity | 23 | 4.79E-04 |
| RNA binding | 33 | 6.95E-04 |
| Thiol-dependent ubiquitin-specific protease activity | 14 | 7.26E-04 |
| Znc ion binding | 93 | 1.11E-03 |
| 1-phosphatidylinositol binding | 6 | 1.30E-03 |
| Receptor signaling protein serine/threonine kinase activity | 11 | 2.78E-03 |
| DNA binding | 59 | 4.38E-03 |
GO gene ontology, BP biological process, CC cellular component, MF molecular function