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. 2020 Jun 3;20:506. doi: 10.1186/s12885-020-06863-9

Table 5.

GO enrichment analysis results for miR-106b

BP
 GO terms Genes P-value
  Transcription, DNA-templated 309 4.29E-12
  Protein ubiquitination 82 1.53E-10
  Negative regulation of transcription from RNA polymerase II promoter 135 3.84E-10
  Viral process 66 4.52E-08
  Protein polyubiquitination 47 5.79E-08
  Protein ubiquitination involved in ubiquitin-dependent protein catabolic process 41 1.15E-07
  Cellular response to DNA damage stimulus 49 4.09E-07
  Cell-cell adhesion 59 4.12E-07
  Positive regulation of transcription, DNA-templated 94 7.99E-07
  Positive regulation of transcription from RNA polymerase II promoter 157 8.43E-07
CC
GO terms Genes P-value
  Nucleoplasm 509 4.53E-41
  Nucleus 817 4.14E-36
  Cytoplasm 762 8.37E-28
  Cytosol 512 2.68E-22
  Membrane 337 2.06E-13
  Nucleolus 153 6.39E-11
  Cell-cell adherens junction 70 8.52E-09
  Intracellular membrane-bounded organelle 100 1.50E-07
  Midbody 35 3.50E-07
 Perinuclear region of cytoplasm 103 3.83E-06
MF
GO terms Genes P-value
  Protein binding 1251 6.93E-44
  Poly(A) RNA binding 211 5.55E-15
  Ubiquitin-protein transferase activity 81 5.55E-12
  Ubiquitin protein ligase binding 70 2.73E-10
  Ubiquitin protein ligase activity 52 5.74E-10
  Cadherin binding involved in cell-cell adhesion 67 7.22E-09
  Transcription factor activity, sequence-specific DNA binding 155 1.02E-06
  DNA binding 246 1.35E-06
  ATP binding 221 3.40E-06
  Protein serine/threonine kinase activity 72 4.18E-06

GO gene ontology, BP biological process, CC cellular component, MF molecular function