Table 5.
GO enrichment analysis results for miR-106b
| BP | ||
|---|---|---|
| GO terms | Genes | P-value |
| Transcription, DNA-templated | 309 | 4.29E-12 |
| Protein ubiquitination | 82 | 1.53E-10 |
| Negative regulation of transcription from RNA polymerase II promoter | 135 | 3.84E-10 |
| Viral process | 66 | 4.52E-08 |
| Protein polyubiquitination | 47 | 5.79E-08 |
| Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | 41 | 1.15E-07 |
| Cellular response to DNA damage stimulus | 49 | 4.09E-07 |
| Cell-cell adhesion | 59 | 4.12E-07 |
| Positive regulation of transcription, DNA-templated | 94 | 7.99E-07 |
| Positive regulation of transcription from RNA polymerase II promoter | 157 | 8.43E-07 |
| CC | ||
| GO terms | Genes | P-value |
| Nucleoplasm | 509 | 4.53E-41 |
| Nucleus | 817 | 4.14E-36 |
| Cytoplasm | 762 | 8.37E-28 |
| Cytosol | 512 | 2.68E-22 |
| Membrane | 337 | 2.06E-13 |
| Nucleolus | 153 | 6.39E-11 |
| Cell-cell adherens junction | 70 | 8.52E-09 |
| Intracellular membrane-bounded organelle | 100 | 1.50E-07 |
| Midbody | 35 | 3.50E-07 |
| Perinuclear region of cytoplasm | 103 | 3.83E-06 |
| MF | ||
| GO terms | Genes | P-value |
| Protein binding | 1251 | 6.93E-44 |
| Poly(A) RNA binding | 211 | 5.55E-15 |
| Ubiquitin-protein transferase activity | 81 | 5.55E-12 |
| Ubiquitin protein ligase binding | 70 | 2.73E-10 |
| Ubiquitin protein ligase activity | 52 | 5.74E-10 |
| Cadherin binding involved in cell-cell adhesion | 67 | 7.22E-09 |
| Transcription factor activity, sequence-specific DNA binding | 155 | 1.02E-06 |
| DNA binding | 246 | 1.35E-06 |
| ATP binding | 221 | 3.40E-06 |
| Protein serine/threonine kinase activity | 72 | 4.18E-06 |
GO gene ontology, BP biological process, CC cellular component, MF molecular function