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. 2020 Jun 3;20:210. doi: 10.1186/s12935-020-01298-5

Fig. 6.

Fig. 6

Expression of HSD17B6 is regulated by HNF4A. ad Correlation of HSD17B6 expression with HNF4A expression in TCGA and ICGC-LIRI-JP liver datasets. e HNF4A knockout effect on HSD17B6 expression in the embryonic liver. f HNF4A binds to HSD17B6 enhancer and promoter region. Re-analysis of HNF4A ChIP-seq data available in CistromeDB platform. HNF4A chromatin immunoprecipitation was performed in HepG2 (liver cancer derived), and the presence of DNA peaks was evaluated in HSD17B6 enhancer and promoter regions