Table 3.
CTNNB1 mutation in HCC cases according to demographic and pathological characteristics
Characteristics | CTNN mutation N (%) | P |
---|---|---|
Male | 14 (17.7) | 0.575 |
Female | 5 (19.2) | |
Age | ||
40 > | 1 (12.5) | 0.034a |
40–50 | 1 (9.1) | |
51–60 | 4 (16.6) | |
> 60 | 13 (21) | |
Differentiation | ||
Well | 9 (28.1) | 0.097b |
Moderate | 5 (16.7) | |
Poorly | 4 (15.4) | |
Un-known | 1 (5.9) | |
LC-HCC | ||
Yes | 4 (14.8) | 0.423 |
No | 15 (19.2) |
aThe frequency of mutations was significantly increased toward aging, bThe rate of mutations in well differentiated tumors was higher than others