Table 3.

Multiple regression analysis of serum creatinine levels at renal biopsy and histological variables

Variable	Model 1	Model 2	Model 3
	Coeff [95% CI]	Coeff [95% CI]	Coeff [95% CI]
Active lesions
Endocapillary proliferation	0.15 [− 0.22 to 0.51]	0.16 [− 0.20 to 0.52]	0.16 [− 0.2 to 0.52]
Karyorrhexis	0.08 [− 1.34 to 1.51]	0.20 [− 0.74 to 1.15]	0.23 [− 0.71 to 1.17]
Fibrinoid necrosis	0.18 [− 1.08 to 1.45]
Rupture of glomerular basement membranes	0.16 [− 3.54 to 3.85]	0.34 [− 2.83 to 3.52]	0.39 [− 2.79 to 3.56]
Extracapillary proliferation	0.37 [− 0.77 to 1.51]	0.40 [− 0.73 to 1.52]	0.42 [− 0.7 to 1.54]
Wire loop lesions	0.13 [− 0.22 to 0.48]	0.12 [− 0.22 to 0.47]	0.08 [− 0.26 to 0.42]
Hyaline deposits	−1.84 [− 3.64 to − 0.04]	− 1.78 [− 3.56 to − 0.00]	− 1.67 [− 3.43 to 0.09]
Membranous lesions	−0.17 [− 0.50 to 0.17]	−0.19 [− 0.51 to 0.13]	−0.15 [− 0.48 to 0.17]
Monocellular infiltration (category)	0.22 [− 0.36 to 0.80]		0.26 [0.04 to 0.47]
Chronic lesions
Glomerular sclerosis	1.10 [0.43 to 1.76]	1.08 [0.43 to 1.74]	1.07 [0.43 to 1.72]
Fibrous adhesion	0.73 [−0.69 to 2.14]	0.68 [−0.72 to 2.08]	0.79 [− 0.61 to 2.19]
Fibrous crescents	−1.30 [− 3.91 to 1.31]	−1.31 [− 3.84 to 1.21]	− 1.32 [− 3.84 to 1.21]
Interstitial fibrosis (category)	0.06 [− 0.52 to 0.65]	0.27 [0.05 to 0.49]
Arteriosclerosis (category)	− 0.04 [− 0.29 to 0.21]	−0.02 [− 0.26 to 0.23]	− 0.02 [− 0.26 to 0.23]

Covariates; Model 1: all independent explanatory variables; Model 2: explanatory variables excluding fibrinoid necrosis and monocellular infiltration; Model 3: explanatory variables excluding fibrinoid necrosis and interstitial fibrosis. Coeff β-Coefficient; CI Confidential interval