Table 4.

Hazard ratios (HRs) of disease-free survival and mortality, and corresponding 95% of confidence intervals (CIs), according to histologic subtypes, among 1009 “Triple Negative” breast cancer. Sardinia, Italy 1994–2015

	Disease-free survival		Overall survival
	Univariate analysis HR (95% CI)	Multivariate analysisa HR (95% CI)	Univariate analysis HR (95% CI)	Multivariate analysisa HR (95% CI)
IBC-NST	1.00b	1.00b	1.00b	1.00b
Lobular	0.68 (0.33–1.39)	0.57 (0.26–1.24)	1.36 (0.79–2.33)	1.06 (0.50–2.25)
Apocrine	1.40 (0.76–2.60)	1.34 (0.71–2.49)	0.77 (0.64–1.76)	0.54 (0.17–1.73)
Adenoid cystic	1.85 (0.46–7.50)	1.20 (0.16–8.69)	–	–
Metaplastic	0.85 (0.40–1.83)	0.75 (0.34–1.64)	0.88 (0.39–2.01)	0.60 (0.18–1.96)
Medullary	0.13 (0.01–0.92)	0.12 (0.01–0.87)	0.30 (0.07–1.21)	0.42 (0.10–1.74)
Other	1.44 (0.67–3.09)	1.33 (0.61–2.89)	0.64 (0.20–2.04)	0.17 (0.02–1.28)

^aEstimates from multivariate proportional hazard regression model adjusted for age, tumor size and number of positive nodes. Estimates in bold are those significant at the 0.05 level

^bReference category