Table 4.
Magnitude of nocturnal BP dipping correlates with vascular function and subclinical atherosclerosis
| Measure | N | % SBP Dip | % DBP Dip | SBP load | DBP load | ||||
|---|---|---|---|---|---|---|---|---|---|
| r | p value | r | p value | ρ | p value | ρ | p value | ||
| Aortic stiffness | |||||||||
| PWV SDS | 18 | 0.3 | 0.29 | − 0.1 | 0.76 | 0.3 | 0.28 | 0.0 | 0.87 |
| Augmentation index | 18 | 0.3 | 0.30 | 0.3 | 0.31 | 0.6 | 0.01 | 0.7 | < 0.01 |
| Endothelial function | |||||||||
| lnRHI | 16 | 0.2 | 0.49 | 0.5 | 0.04 | − 0.2 | 0.50 | − 0.2 | 0.44 |
| Wall thickening | |||||||||
| CCA-IMT | 18 | − 0.5 | 0.06 | − 0.2 | 0.49 | − 0.1 | 0.62 | − 0.3 | 0.27 |
| Mean cIMT | 14 | − 0.6 | 0.03 | − 0.1 | 0.72 | − 0.2 | 0.51 | − 0.1 | 0.79 |
Pearson’s correlation coefficients (r) estimating the relationship between the percent dip in nocturnal BP and measures of vascular function and subclinical atherosclerosis; Spearman rank correlations (ρ) were used to assess associations with 24-h BP load
SBP systolic blood pressure, DBP diastolic blood pressure, PWV SDS pulse wave velocity standard deviation score for age and sex, lnRHI reactive hyperemia index, CCA-IMT mean common carotid intima-media thickness, Mean cIMT mean of IMT measurements over 6 carotid sites