Table 4.
Univariate and multivariate Cox regression analysis of TCGA-LIHC patients
| Characteristics | Univariate Cox | Multivariate Cox | ||
|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | |
| Risk score | 2.948 (1.752–4.961) | 0.000 | 2.349 (1.289–4.279) | 0.005 |
| Age (years) | ||||
| < 60 | 1 | 1 | ||
| ≥ 60 | 1.535 (0.923–2.552) | 0.099 | 1.593 (0.935–2.714) | 0.086 |
| Sex | ||||
| Female | 1 | |||
| Male | 0.673 (0.405–1.119) | 0.127 | 1.023 (0.588–1.779) | 0.936 |
| BMI (kg/m2) | ||||
| < 25 | 1 | – | – | |
| ≥ 25 | 1.214 (0.738–1.999) | 0.445 | – | – |
| G stage | ||||
| G1 + G2 | 1 | 1 | ||
| G3 + G4 | 1.536 (0.930–2.536) | 0.094 | 1.364 (0.791–2.352) | 0.265 |
| Residual tumor | ||||
| R0 | 1 | – | – | |
| Non-R0 | 1.328 (0.413–4.278) | 0.634 | – | – |
| AJCC stage | ||||
| I + II | 1 | 1 | ||
| III + IV | 2.271 (1.321–3.904) | 0.003 | 2.219 (1.215–3.734) | 0.008 |
| Vascular invasion | ||||
| No | 1 | 1 | ||
| Yes | 1.760 (1.048–2.958) | 0.033 | 1.266 (0.730–2.196) | 0.401 |
| AFP (ng/ml) | ||||
| < 300 | 1 | – | – | |
| ≥ 300 | 1.171 (0.668–2.054) | 0.581 | – | – |