Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Impact of the DIPG environment on the transport of drugs across the BBB and BBTB. Endothelial permeability coefficient of the chemotherapeutic compounds a temozolomide and b panobinostat, after 7 days of incubation of the BBB cells with astrocytes (control), or DIPG cell lines DIPG-007, DIPG-013 and DIPG-014. c For each condition, the endothelial permeability coefficient (Pe) and the mass balance (MB) of the compounds were calculated. **p < 0.01; *p < 0.05. N = 2; n = 6
