Table 1.
Characteristics of the Study Population (N = 113)
| Characteristic | Value |
|---|---|
| Age, median (IQR), y | 61 (15) |
| Female sex | 66 (58%) |
| Race | |
| White | 97 (86%) |
| Black | 4 (3.5%) |
| Asian/Pacific Islander | 9 (8.0%) |
| Hispanic or Latino | 3 (2.7%) |
| BMI, median (IQR), kg/m2 | 28 (9) |
| No. of comorbidities | |
| 0 | 19 (17%) |
| 1 | 30 (27%) |
| 2 | 35 (31%) |
| ≥ 3 | 29 (25%) |
| Smoking status | |
| Never | 35 (31%) |
| Former | 51 (45%) |
| Current | 27 (24%) |
| Pack-years, median (IQR), ya | 27 (35) |
| Years since quit, median (IQR)b | 16 (20) |
| Personal history of extrathoracic malignancy | 10 (8.9%) |
| Personal history of thoracic radiation therapy | 4 (3.5%) |
| Family history of lung cancer | 25 (22%) |
| Previous imaging available | 38 (34%) |
| Indication for CT imagingc | |
| Chest radiographic abnormality | 35 (31%) |
| Cough | 26 (23%) |
| Dyspnea | 24 (21%) |
| Chest pain | 14 (12%) |
| Other | 45 (40%) |
| Nodule characteristicsd | |
| Size | |
| Median (IQR), mm | 8 (13) |
| ≤ 4 mm | 20 (18%) |
| > 4-6 mm | 22 (20%) |
| > 6-8 mm | 17 (15%) |
| > 8 mm | 54 (48%) |
| More than 1 nodule | 69 (61%) |
| Density | |
| Solid | 98 (88%) |
| Partially solid | 12 (11%) |
| Ground-glass opacity | 3 (2.7%) |
| Spiculated | 29 (26%) |
| Lobar location of nodule | |
| Upper lobes | 58 (51%) |
| Lower lobes | 47 (42%) |
| Spans multiple lobes | 1 (0.88%) |
| Not reported | 7 (6.2%) |
| Year | |
| 2010 | 39 (35%) |
| 2011 | 39 (35%) |
| 2012 | 35 (31%) |
| Median follow-up (IQR), ye | 4.4 (1.8) |
IQR = interquartile range.
a
Among 78 current or former smokers.
b
Among 51 former smokers.
c
Columns may not add to 100% because patients may have multiple conditions or indications.
d
Refers to the dominant nodule.
e
Follow-up < 3 years is due to death.