Table 2.
Correlations Between Biomarkers and Continuous Clinical Variables, Limited to Subjects With Biomarkers Obtained Within 3 Months of Clinical Tests: n = 191
| Variable | log NT-proBNP | log Gal3 | log ST2 |
|---|---|---|---|
| Demographics | |||
| Age, y | 0.39; < .001 | 0.32; < .001 | 0.12; .09 |
| 6MWD, m | –0.36; < .001 | –0.28; .006 | –0.31; .002 |
| Hemodynamics | |||
| RAP, mm Hg | 0.40; < .001 | 0.14; .05 | 0.37; < .001 |
| mPAP, mm Hg | 0.23; .001 | –0.05; .51 | 0.13; .07 |
| PAWP, mm Hg | 0.09; .22 | 0.09; .21 | 0.06; .41 |
| PVR, Wood units | 0.26; < .001 | –0.003; .97 | 0.18; .02 |
| Cardiac output, L/min | –0.20; .006 | –0.10; .19 | –0.11; .14 |
| Cardiac index, L/min/m2 | –0.22; .003 | –0.13; .09 | –0.14; .06 |
| Stroke volume, L | –0.21; .016 | –0.24; .008 | –0.15; .10 |
| PA compliance, mL/mm Hg | –0.26; .004 | –0.08; .37 | –0.09; .34 |
| Transpulmonary gradient, mm Hg | 0.23; .002 | –0.06; .43 | 0.12; .12 |
| Diastolic pulmonary gradient, mm Hg | 0.19; .01 | –0.03; .67 | 0.16; .03 |
| RV stroke work, mm Hg × L | –0.16; .07 | –0.32; < .01 | –0.14; .13 |
| RV stroke work index, g/m2/beat | –0.16; .06 | –0.33; < .01 | –0.16; .07 |
| RV power, mm Hg × L/min | –0.18; .05 | –0.05; .59 | –0.08; .38 |
All data are presented as follows: Spearman correlation coefficient; P value. PA = pulmonary arterial; RV = right ventricular. See Table 1 legend for expansion of other abbreviations.