Table 4.
Cox Multivariable Hazard Ratios for Mortalitya
| Cohort | log NT-proBNP | log Gal3 | log ST2 |
|---|---|---|---|
| Overall cohort | 1.84, 1.62-2.10; < .001 | 1.12, 0.85-1.47; .44 | 2.79, 2.21-3.53; < .001 |
| CTD-PAH subgroup | 1.74, 1.42-2.14; < .001 | 0.92, 0.59-1.44; .72 | 3.48, 2.30-5.26; < .001 |
| IPAH subgroup | 2.48, 1.90-3.23; < .001 | 1.33, 0.80-2.20; .27 | 3.92, 2.56-6.00; < .001 |
All data are presented as follows: hazard ratio, 95% CI; P value. See Table 1 legend for expansion of abbreviations.
Each model was adjusted for age, sex, subtype of PAH, PAH-specific therapy, NYHA FC, 6MWD, RAP, mPAP, cardiac index, and PVR.