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. 2020 Jun 3;39:102. doi: 10.1186/s13046-020-01602-1

Table 2.

Histopathological examination of tongue lesions in various 4NQO-treated mice groups

Group Mice No. Normal epithelial Hyperplasia Dysplasia Squamous cell carcinoma
Mild Moderate Severe
Vehicle 8 0 1 (12.5%) 1 (12.5%) 1 (12.5%) 1 (12.5%) 4 (50%)
VP 8 0 2 (25%) 1 (12.5%) 2 (25%) 2 (25%) 1 (12.5%)