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. 2020 Jun 3;21:122. doi: 10.1186/s12881-020-01036-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Schematic genomic structure of the OPG gene with the positions of the studied polymorphisms. The filled boxes indicate the protein-coding regions and the white boxes indicate the untranslated regions. The variants (rs2228568, rs7844539, rs3102734 and rs2073618) locations within the OPG gene are marked with arrows. The sizes of exons/introns and positions of the variants within the OPG gene are proportional to the original gene size according to the USC Genome Browser (GRCh37/hg19)