Table 2.
Correlation between radiation exposure and cytokine dysregulation
| Subjects beyond reference range | Control, n (%) | Exposed, n (%) | P-value |
|---|---|---|---|
| Tumor necrosis factor-α | 10 (24) | 18 (55) | 0.0085 |
| Monocyte chemoattractant protein-1 | 10 (24) | 25 (76) | <0.0001 |
| Interleukin-10 | 10 (24) | 25 (76) | <0.0001 |
| Interleukin-6 | 10 (24) | 5 (15) | 0.4 |
| Interleukin-8 | 10 (24) | 2 (6) | 0.06 |
n, Number of participants. Values beyond the reference range: exceeding the 75-percentile of the control group for MCP-1 (≥193 pg/ml), TNFα (≥5.5 pg/ml), IL-6 (≥9.65 pg/ml), IL-8 (≥10.77 pg/ml); and below the 25-percentile for IL-10 (≤ 6.5 pg/ml). The incidence of dysregulated cytokines was analyzed by Fisher’s exact test of independence.