Fig. 3.

CYP24A1 expression a. No significant difference in CYP24A1 mRNA levels was observed between COPD explant tissue and tissue from unused donor lungs (p = 0.07). b. CYP24A1 protein expression was not altered in COPD explant tissue compared to tissue from unused donor lungs. CYP24A1 staining in bronchial epithelium of an unused donor lung (c) and COPD explant lung (d). Positive endothelial staining in an unused donor lung (e) and COPD explant lung (f). Positive immune cell staining in an unused donor lung (g) and COPD explant lung (h). Representative images are shown. N = 10 Horizontal line represents the median value