Table 2.

Reviewed Studies on SDF and AgNPs categorized as per the primary and secondary objectives of the review

		Silver diamine fluoride (SDF)	Nano silver particles (AgNPs)
In vivostudies Primary objective: To systematically review the clinical application and antimicrobial potential of silver-containing formulation for caries arrest	RCT	Mitwalli et al., 2019 Milgrom et al., 2018 Karched et al., 2019	Santos et al., 2014
	Systematic review- RCTs	Urquhart et al., 2019 Trieu et al., 2019	(nil)
	Umbrella review	Seifo et al., 2019	(nil)
In vitrostudies Secondary objective: To summarize the available in vitro evidence of microbicidal efficacy of silver-containing formulations against ‘cariogenic’ microbiota in dentine	In vitrostudies	Mei et al., 2013(a) Chu et al., 2012 Mei et al., 2013(b) Hamama et al., 2015	Besinis et al., 2014 Schwass et al., 2018
	Systematic review onin vitrostudies	(nil)	Noronha et al., 2017