Table 1.
Patient characteristics and clinical parameters
| Parameter | All patients (n = 820) |
|---|---|
| Demographics | |
| Age, median [IQR] | 65 [52–75] |
| Male gender, n (%) | 511 (62) |
| BMI, n (%) | |
| < 20 | 34 (4) |
| 20 to < 25 | 225 (29) |
| 25 to < 30 | 255 (33) |
| 30 to < 40 | 200 (26) |
| 40 or more | 53 (7) |
| Reason for ICU admission | |
| Medical (%) | 73.2 |
| Surgical (%) | 26.8 |
| Admission diagnosis | |
| Sepsis (%) | 38.7 |
| Post cardiac surgery (%) | 4.1 |
| Post vascular surgery (%) | 6.7 |
| Post non-cardiovascular surgery (%) | 9.5 |
| Cardiac arrest (%) | 3.1 |
| Cardiac emergency without cardiac arrest (%) | 14.5 |
| Neurological emergency (%) | 2.3 |
| Gastrointestinal emergency (%) | 6.7 |
| Acute kidney injury (%) | 3.6 |
| Decompensated liver disease (%) | 4.6 |
| Others (%) | 6.2 |
| Comorbidities (%) | |
| Hypertension | 56.4 |
| Heart disease | 49.5 |
| Diabetes mellitus | 35.6 |
| Chronic kidney disease | 43.3 |
| Cancer | 20.2 |
| Chronic obstructive pulmonary disease | 18.4 |
| Chronic liver disease | 14.2 |
| Parameters at initiation of CRRT | |
| SOFA score, mean (SD) | 10.4 (3.8) |
| Arterial lactate concentration [mmol/l], median [IQR] | 3 [1.8–6.5] |
| Treatment with vasopressor, n (%) | 588 (72) |
| Hb [g/dl], median [IQR] | 9.8 [8.8–11] |
| Cumulative fluid balance [ml], median [IQR] | 1772 [336–4536] |
| Outcomes | |
| ICU mortality, n (%) | 264 (32) |
| Hospital mortality, n (%) | 331 (40) |
Abbreviations: BMI body mass index, ICU intensive care unit, IQR interquartile range, CRRT continuous renal replacement therapy, SOFA Sequential Organ Failure Assessment, Hb haemoglobin, SD standard deviation