Table 1.
Top 20 most abundant proteins identified in MOMVs
| Rank | Protein accession | Gene name | Protein annotation | Subcellular localization | Biological function | MW (kDa) | Intensity |
|---|---|---|---|---|---|---|---|
| 1 | P0A910 | ompA | Outer membrane protein A | Outer membrane | Cell wall/membrane/envelope biogenesis | 37.2 | 7.57E+11 |
| 2 | P69776 | lpp | Major outer membrane prolipoprotein Lpp | Outer membrane | Cell wall/membrane/envelope biogenesis | 8.3234 | 6.39E+11 |
| 3 | P06996 | ompC | Outer membrane protein C | Outer membrane | Cell wall/membrane/envelope biogenesis | 40.368 | 4.83E+11 |
| 4 | P0A903 | bamC | Outer membrane protein assembly factor BamC | Outer membrane | Cell wall/membrane/envelope biogenesis | 36.842 | 3.39E+11 |
| 5 | P0A6F5 | groL | 60 kDa chaperonin | Cytoplasmic | Posttranslational modification, protein turnover, chaperones | 57.328 | 3.07E+11 |
| 6 | P0A905 | slyB | Outer membrane lipoprotein SlyB | Outer membrane | Cell wall/membrane/envelope biogenesis | 15.601 | 1.87E+11 |
| 7 | P0A917 | ompX | Outer membrane protein X | Outer membrane | Cell wall/membrane/envelope biogenesis | 18.602 | 9.60E+10 |
| 8 | P0A908 | mipA | MltA-interacting protein | Outer membrane | Cell wall/membrane/envelope biogenesis | 27.831 | 8.14E+10 |
| 9 | P61320 | lolB | Outer-membrane lipoprotein LolB | Outer membrane | Cell wall/membrane/envelope biogenesis | 23.55 | 6.45E+10 |
| 10 | P0A915 | ompW | Outer membrane protein W | Outer membrane | Cell wall/membrane/envelope biogenesis | 22.928 | 5.63E+09 |
| 11 | P06959 | aceF | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | Cytoplasmic | Energy production and conversion | 66.095 | 5.45E+09 |
| 12 | P09394 | glpQ | Glycerophosphodiester phosphodiesterase | Periplasmic | Energy production and conversion | 40.843 | 4.41E+09 |
| 13 | P13036 | fecA | Fe (3 +) dicitrate transport protein FecA | Outer membrane | Inorganic ion transport and metabolism | 85.321 | 4.02E+09 |
| 14 | P0A940 | bamA | Outer membrane protein assembly factor BamA | Outer membrane | Cell wall/membrane/envelope biogenesis | 90.552 | 2.09E+09 |
| 15 | P31554 | lptD | LPS-assembly protein LptD | Outer membrane | Cell wall/membrane/envelope biogenesis | 89.67 | 9.78E+08 |
| 16 | P06971 | fhuA | Ferrichrome outer membrane transporter/phage receptor | Outer membrane | Inorganic ion transport and metabolism | 82.181 | 7.20E+08 |
| 17 | P21420 | nmpC | Putative outer membrane porin protein NmpC | Outer membrane | Cell wall/membrane/envelope biogenesis | 40.302 | 7.03E+08 |
| 18 | P0AFG8 | aceE | Pyruvate dehydrogenase E1 component | Cytoplasmic | Energy production and conversion | 99.667 | 6.63E+08 |
| 19 | P21513 | rne | Ribonuclease E | Cytoplasmic | Translation, ribosomal structure and biogenesis | 118.2 | 6.48E+08 |
| 20 | P00968 | carB | Carbamoyl-phosphate synthase subunit beta | Periplasmic | Membrane biogenesis/synthesize carbamoyl phosphate | 117.842 | 4.28E+08 |
MOMVs represents multi-serogroup outer membrane vesicles derived from avian pathogenic Escherichia coli