Table 3.
Association between decision-making factors and the strength of recommendations
| Mixed-effect model [logistic regression] | Dependent variable: weak for; strong for odds ratio (OR) with 95% confidence interval (CI) |
|---|---|
| Fixed effect | |
| Role: chair (reference category) | |
| Methodologist | 0.06 (95% CI 0–.85; P = .04) |
| Patient representative | 0.64 (95% CI .03–12.4; P = .77) |
| Panel member | 1.15 (95% CI .23–5.89; P = .87) |
| Vulnerable population | |
| Yes vs. no | 1.83 (95% CI .56–5.91; P = .31) |
| Pressured to ”vote” certain way | 2.27 (95% CI .21–24.9; P = .5) |
| Recused from ”voting” | |
| Yes vs. no | 1.18 (95% CI .4–3.45; P = .76) |
| Age (per decade) | 2.6 (95% CI .99–7.93; P = .079) |
| Sex | |
| Female vs. male | 0.55 (95% CI .20–1.48; P = .24) |
| Experience (years in management of given condition) | 0.89 (95% CI .76–.99; P = .047) |
| Expertise (consider oneself with higher, same or low expertise than most other experts) | 1.40 (95% CI .566–3.49; P = .47) |
| Exposure (# of patients per month with given condition) | 0.89 (95% CI .61–1.31; P = .57) |
| Objectivism (tendency to seek empirical information) | 1.64 (95% CI .44–6.10; P = .46) |
| Tendency toward rational (analytical) thinking | 0.51 (95% CI .15–1.76; P = .23) |
| Tendency toward experiential-intuitive thinking | 0.89 (95% CI .37–2.15; P = .79) |
| Satisficing (tendency to accept “good” enough solution | 2.23 (95% CI .61–8.1; P = .23) |
| Maximizing(decision difficulty)-degree difficulty experienced when making choices among abundant options | 2.14 (95% CI .99–4.65; P=.05) |
| Maximizing(alternative search)-tendency to expand resources in search for best possible solution | 0.65 (95% CI .31–1.35; P = .25) |
| Intolerance of uncertainty | 0.4 (95% CI .13–1.21; P = .11) |
| Regret of making a wrong recommendation | 0.99 (95% CI .95–1.05; P = .89) |
| Certainty in Evidence | 3.61 (95% CI 2.17–6.01; P < 0.001) |
| Importance of patients’ values and preferences | 2.33 (95% CI 1.34–4.07; P = .003) |
| Balance between benefits and harms | 18.3 (95% CI 7.68–43.7; P = .000) |
| Importance of cost and resources | 1.83 (95% CI 1.25–2.67; P = .002) |
| Random intercepts | |
| Panel (variance) | 3.14 × 10−32 |
| Participant within panel (variance) | 1.00 × 10−33 |
Bolded text refers to statistically significant findings.