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. Author manuscript; available in PMC: 2020 Jun 3.
Published in final edited form as: Nat Biomed Eng. 2019 Oct;3(10):766–767. doi: 10.1038/s41551-019-0443-y

Fig. 1 |. Effect of TREG cells on immune cells.

Fig. 1 |

TREG cells are developed in the thymus (central TREG cells; cTREG) or generated and expanded outside the thymus (peripheral TREG cells; pTREG); can directly target antigen-presenting cells, NK cells and effector T cells; and mediate immunosuppression via distinct molecular mechanisms.