Table 4.

Top 10 GO protein classifications.

Protein categories	Term	Representative protein(s)	P-value
Biological processes
	Platelet degranulation	Platelet basic protein	2.56 × 10−53
	Protein activation cascade	Complement C1 subunits	2.78 × 10−52
	Acute inflammatory response	Complement factors	1.34 × 10−45
	Defense response	LPS-binding protein	1.16 × 10−38
	Regulation of proteolysis	Carboxypeptidase B2	4.67 × 10−38
	Complement activation	Immunoglobulin	1.56 × 10−37
	Proteolysis	Plasma serine protease inhibitor	9.36 × 10−37
	Vesicle-mediated transport	Apolipoprotein D	2.77 × 10−36
	Response to stress	Galectin-3-binding protein	2.46 × 10−35
	Inflammatory response	Serum amyloid A	2.72 × 10−35
Molecular function
	Endopeptidase inhibitor activity	Kallistatin	1.37 × 10−31
	Endopeptidase regulator activity	Protein AMBP	3.94 × 10−31
	Peptidase inhibitor activity	Inter-alpha-trypsin inhibitor	6.59 × 10−31
	Peptidase regulator activity	Kininogen-1	6.85 × 10−30
	Enzyme inhibitor activity	Alpha-1-antichymotrypsin	4.55 × 10−27
	Serine-type endopeptidase inhibitor activity	Protein Z-dependent protease inhibitor	1.27 × 10−25
	Enzyme regulator activity	Angiotensinogen	2.23 × 10−18
	Serine-type endopeptidase activity	Prothrombin	1.53 × 10−16
	Glycosaminoglycan binding	Thrombospondin	5.25 × 10−16
	Serine-type peptidase activity	Plasminogen	8.45 × 10−16

^*LPS; lipopolysacharide