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(a) Free-floating co-culture spheroid of cancer cells and fibroblasts generated using the ATPS technology. (b) Proliferation of TNBC cells in co-culture spheroids containing normal human mammary fibroblasts (HMF) or activated human mammary fibroblasts (CXCL12+HMFs) by quantifying Ki-67+ TNBC cells. *p < 0.05. Panels a and b are reproduced with permission from Oncotarget, 2018;9:249. (A color version of this figure is available in the online journal.)
