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(a) Invasion of TNBC cells from co-culture spheroids into the collagen matrix. (b) Matrix invasion of TNBC cells inhibited by using AMD3100. *p < 0.05. (c) Normal human mammary fibroblasts (red) segregate from TNBC cells (green), while CXCL12-secreting fibroblasts (red) remain mixed with TNBC cells. Panels a, b, and c are reproduced with permission from Advanced Therapeutics, 2019; 2:1900121. (A color version of this figure is available in the online journal.)
