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. 2020 Mar 30;215(2):483–495. doi: 10.1534/genetics.120.303125

Figure 5.

Figure 5

Identification of transcription factors mediating effects on rolling behavior. (A) RNAi mediated knockdown of individual transcription factors in rol-6(su1006)T animals. Significant differences (P <0.05) in rolling relative to control are shown in orange. Knockdown of tbx-2 and elt-3 significantly increased and decreased (respectively) rolling in LMN40 rol-6(su1006)T animals. (B) Knockdown of tbx-2 and elt-3 also significantly increased, and decreased (respectively) rolling in ERT60 rol-6(su1006)T animals. (C) Knockdown of tbx-2 and elt-3 produce the opposite effect on rolling in sqt-3(sc8) mutants than in rol-6(su1006)T animals. Statistical analysis with one-way ANOVA and Dunnett’s multiple comparison test. Asterisks indicate P-values (* P <0.05, ** P <0.005).